What are the top benefits of Winidrol?
A variety of compounds used for the treatment of OA, including steroidal and non-steroidal drugs, inhibitor of nitric oxide production (NO) ( Saleri et al. 2004 ). NO may be responsible for cartilage destruction in OA ( Blanco et al. 1995 ), by damaging chondrocyte function, inhibiting collagen and proteoglycan synthesis, activating metalloproteinase, decreasing the expression of IL-1 receptor antagonist, inhibiting chondrocyte proliferation, and inducing apoptotic death ( Studer et al. 1999 ). Stanozolol is a synthetic derivative of testosterone; its properties include anabolic/androgenic activity ( Zannetti, 2004 ), probably associated with its affinity for androgenic and, at lower doses, glucocorticoid receptors ( Fernandez et al. 1994 ). Because of its strong anabolic effects, studies on the effects of stanozolol treatment on OA are not performed in human medicine (Belch et al. 1986 and Ellis et al. 1994 ): the same promising results (Zannetti, 2004. Dondi et al. 2008 and Adamama-Moraitou et al. 2009 ) has led to renewed interest in the use of the product in veterinary medicine for companion animals.
Anabolic steroids cause retention of nitrogen, sodium, potassium, chloride, water and phosphorus, and decrease urinary excretion of calcium. Patients should be instructed to report edema. [Ref ]